发明授权
- 专利标题: Method for detecting the presence of P-selectin
- 专利标题(中): 检测P-选择蛋白存在的方法
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申请号: US964690申请日: 1997-11-05
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公开(公告)号: US6033667A公开(公告)日: 2000-03-07
- 发明人: Robert W. Chesnut , Margaret J. Polley , James C. Paulson , S. Tarran Jones , Jose W. Saldanha , Mary M. Bendig , Michael Kriegler , Carl Perez , Robert Bayer , Michael Nunn
- 申请人: Robert W. Chesnut , Margaret J. Polley , James C. Paulson , S. Tarran Jones , Jose W. Saldanha , Mary M. Bendig , Michael Kriegler , Carl Perez , Robert Bayer , Michael Nunn
- 申请人地址: CA San Diego
- 专利权人: Cytel Corporation
- 当前专利权人: Cytel Corporation
- 当前专利权人地址: CA San Diego
- 优先权: ILX105614 19930505
- 主分类号: A61P7/00
- IPC分类号: A61P7/00 ; A61P11/00 ; A61P37/02 ; C07K16/28 ; A61K39/395 ; C07H21/04 ; C12N5/12
摘要:
The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.
公开/授权文献
- US5264576A Pyrazolo[4,3-c]pyridines which are intermediates 公开/授权日:1993-11-23
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