发明授权
- 专利标题： Method for detecting the presence of P-selectin
- 专利标题（中）： 检测P-选择蛋白存在的方法
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申请号： US964690申请日： 1997-11-05
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公开(公告)号： US6033667A公开(公告)日： 2000-03-07
- 发明人: Robert W. Chesnut , Margaret J. Polley , James C. Paulson , S. Tarran Jones , Jose W. Saldanha , Mary M. Bendig , Michael Kriegler , Carl Perez , Robert Bayer , Michael Nunn
- 申请人： Robert W. Chesnut , Margaret J. Polley , James C. Paulson , S. Tarran Jones , Jose W. Saldanha , Mary M. Bendig , Michael Kriegler , Carl Perez , Robert Bayer , Michael Nunn
- 申请人地址： CA San Diego
- 专利权人： Cytel Corporation
- 当前专利权人： Cytel Corporation
- 当前专利权人地址： CA San Diego
- 优先权： ILX105614 19930505
- 主分类号： A61P7/00
- IPC分类号： A61P7/00 ; A61P11/00 ; A61P37/02 ; C07K16/28 ; A61K39/395 ; C07H21/04 ; C12N5/12
摘要：
The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.
公开/授权文献
- US5264576A Pyrazolo[4,3-c]pyridines which are intermediates 公开/授权日：1993-11-23