发明授权
- 专利标题： Antisense inhibition of human Akt-2 expression
- 专利标题（中）： 人类Akt-2表达的反义抑制
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申请号： US256465申请日： 1999-03-23
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公开(公告)号： US6043090A公开(公告)日： 2000-03-28
- 发明人: Brett P. Monia , Lex M. Cowsert
- 申请人： Brett P. Monia , Lex M. Cowsert
- 申请人地址： CA Carlsbad
- 专利权人： Isis Pharmaceuticals Inc.
- 当前专利权人： Isis Pharmaceuticals Inc.
- 当前专利权人地址： CA Carlsbad
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C12N15/113 ; C12Q1/68 ; C07H21/04 ; C12N15/00
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of Akt-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Akt-2. Methods of using these compounds for modulation of Akt-2 expression and for treatment of diseases associated with expression of Akt-2 are provided.