发明授权
- 专利标题： Borna disease virus-specific DNA and proteins
- 专利标题（中）： 伯纳病病毒特异性DNA和蛋白质
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申请号： US222227申请日： 1998-12-29
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公开(公告)号： US6060236A公开(公告)日： 2000-05-09
- 发明人: Janice E. Clements , Opendra Narayan , Susan Vandewoude , Juergen A. Richt
- 申请人： Janice E. Clements , Opendra Narayan , Susan Vandewoude , Juergen A. Richt
- 申请人地址： MD Baltimore
- 专利权人： The Johns Hopkins University School of Medicine
- 当前专利权人： The Johns Hopkins University School of Medicine
- 当前专利权人地址： MD Baltimore
- 主分类号： C07K14/08
- IPC分类号： C07K14/08 ; C12N15/31 ; C12Q1/70
摘要：
Borna disease virus (BDV) causes a rare neurological disease in horses and sheep. A subtractive cDNA expression library was constructed with poly A-selected RNA from a BDV infected MDCK cell line. A clone (B8) was isolated that specifically hybridizes to RNA isolated from BDV-infected brain tissue and BDV-infected cell lines. This clone hybridizes to four BDV-specific positive strand RNAs and one negative strand RNA in BDV-infected rat brain. Nucleotide sequence analysis of the clone suggests that it represents a full length mRNA which contains several open reading frames. The Borna Disease Virus DNA sequences as well as proteins encoded by the BDV DNA sequences are provided.
公开/授权文献
- USD311590S Combination auxiliary brake light and cargo lamp for vehicles 公开/授权日：1990-10-23
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