- 专利标题: Method and apparatus for use with MR imaging
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申请号: US856894申请日: 1997-05-15
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公开(公告)号: US6061587A公开(公告)日: 2000-05-09
- 发明人: John Kucharczyk , Michael E. Moseley
- 申请人: John Kucharczyk , Michael E. Moseley
- 申请人地址: MN Minneapolis
- 专利权人: Regents of the University of Minnesota
- 当前专利权人: Regents of the University of Minnesota
- 当前专利权人地址: MN Minneapolis
- 主分类号: A61B19/00
- IPC分类号: A61B19/00 ; A61M25/00 ; A61M31/00 ; G01R33/28 ; G01R33/563 ; A61B5/05
摘要:
The invention is an apparatus and method for targeted drug delivery into a living patient using magnetic resonance (MR) imaging. The apparatus and method are useful in delivery to all types of living tissue and uses MR Imaging to track the location of drug delivery and estimating the rate of drug delivery. An MR-visible drug delivery device positioned at an target site (e.g., intracranial delivery) delivers a diagnostic or therapeutic drug solution into the tissue (e.g., the brain). The spatial distribution kinetics of the injected or infused drug agent are monitored quantitatively and non-invasively using water proton directional diffusion MR imaging to establish the efficacy of drug delivery at a targeted location.
公开/授权文献
- US5338899A Packaging of electronic devices 公开/授权日:1994-08-16