发明授权
US6071935A Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use as farnesyl protein transferase inhibitors 失效
2-(2-氧代 - 亚乙基) - 咪唑烷-4-酮的衍生物及其作为法呢基蛋白转移酶抑制剂的用途

Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use as
farnesyl protein transferase inhibitors
摘要:
The present invention relates to compounds of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of inhibiting abnormal cell growth, including cancer, in a mammal by administering the compounds of formula I to said mammal.
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