发明授权
US6071953A Sulfonamide-substituted chromans, processes for their preparation, their
use as medicament or diagnostic aid, and medicament comprising them
失效
磺酰胺取代的苯并二氢吡喃染料，其制备方法，它们作为药物或诊断助剂的用途，以及包含它们的药物
- 专利标题： Sulfonamide-substituted chromans, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them
- 专利标题（中）： 磺酰胺取代的苯并二氢吡喃染料，其制备方法，它们作为药物或诊断助剂的用途，以及包含它们的药物
-
申请号： US26513申请日： 1998-02-19
-
公开(公告)号： US6071953A公开(公告)日： 2000-06-06
- 发明人: Hans Jochen Lang , Joachim Brendel , Uwe Gerlach , Klaus Weidmann
- 申请人： Hans Jochen Lang , Joachim Brendel , Uwe Gerlach , Klaus Weidmann
- 申请人地址： DEX Frankfurt am Main
- 专利权人： Hoechst Aktiengesellschaft
- 当前专利权人： Hoechst Aktiengesellschaft
- 当前专利权人地址： DEX Frankfurt am Main
- 优先权： DEX19706675 19970220
- 主分类号： C07D311/60
- IPC分类号： C07D311/60 ; A61K31/35 ; A61K31/352 ; A61P1/00 ; A61P9/00 ; C07D311/68 ; C07D311/70 ; A01N43/16 ; C07D311/74 ; C07D311/76
摘要：
Chromans of formula I ##STR1## with the meanings of R(A), R(B) and R(1) to R(8) stated in the specification are suitable for producing a medicament for blocking the K.sup.+ channel that is opened by cyclic adenosine monophosphate (cAMP); also for producing medicaments for inhibiting gastric acid secretion; for the treatment of ulcers of the stomach and the intestinal region, in particular the duodenum, for the treatment of reflux esophagitis, for the treatment of diarrheal disorders, for the treatment and prevention of all types of arrhythmias, including atrial, ventricular and supraventricular arrhythmias, for controlling reentry arrhythmias and for preventing sudden heart death as a result of ventricular fibrillation.
公开/授权文献
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