发明授权
- 专利标题: Recombinant dengue virus DNA fragment
- 专利标题(中): 重组登革热病毒DNA片段
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申请号: US504878申请日: 1995-07-20
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公开(公告)号: US6074865A公开(公告)日: 2000-06-13
- 发明人: Eileen P. Kelly , Alan D. King
- 申请人: Eileen P. Kelly , Alan D. King
- 申请人地址: DC Washington
- 专利权人: The United States of America as represented by the Secretary of the Army
- 当前专利权人: The United States of America as represented by the Secretary of the Army
- 当前专利权人地址: DC Washington
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K14/18 ; C07H21/04 ; C12N15/85 ; C12N7/00 ; C12N15/00
摘要:
A recombinant protein encompassing the complete envelope glycoprotein and a portion of the carboxy-terminus of the membrane/premembrane protein of dengue 2 virus was expressed in baculovirus as a protein particle. The recombinant protein particle was purified and found to provide protection against lethal challenge with dengue 2 virus in mice.
公开/授权文献
- US4987593A One-show blind signature systems 公开/授权日:1991-01-22
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