发明授权
- 专利标题： Human KDEL receptor
- 专利标题（中）： 人类KDEL受体
-
申请号： US133735申请日： 1998-08-13
-
公开(公告)号： US6103874A公开(公告)日： 2000-08-15
- 发明人: Olga Bandman , Jennifer L. Hillman , Surya K. Goli
- 申请人： Olga Bandman , Jennifer L. Hillman , Surya K. Goli
- 申请人地址： CA Palo Alto
- 专利权人： Incyte Pharmaceuticals, Inc.
- 当前专利权人： Incyte Pharmaceuticals, Inc.
- 当前专利权人地址： CA Palo Alto
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A61K31/7088 ; A61K38/00 ; A61K39/395 ; A61K45/00 ; A61K48/00 ; A61P3/06 ; A61P5/14 ; A61P43/00 ; C07K14/705 ; C07K16/28 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12N15/09 ; C12N15/12 ; C12Q1/68 ; G01N33/566 ; C07K14/00 ; A61K38/16 ; C07H21/04
摘要：
The present invention provides a novel human KDEL receptor (NHKR) and polynucleotides which identify and encode NHKR. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NHKR and a method for producing NHKR. The invention also provides for agonists, antibodies, or antagonists specifically binding NHKR, and their use, in the prevention and treatment of diseases associated with expression of NHKR. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NHKR for the treatment of diseases associated with the expression of NHKR. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NHKR.
公开/授权文献
信息查询
IPC分类:
