发明授权
- 专利标题: Model and method for angiogenesis inhibition
- 专利标题(中): 血管生成抑制的模型和方法
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申请号: US169735申请日: 1998-10-09
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公开(公告)号: US6117862A公开(公告)日: 2000-09-12
- 发明人: Philippe Maria Clotaire Margaron , Simon Leong , Julia G. Levy , Anna M. Richter
- 申请人: Philippe Maria Clotaire Margaron , Simon Leong , Julia G. Levy , Anna M. Richter
- 申请人地址: JPX
- 专利权人: QLT, Inc.
- 当前专利权人: QLT, Inc.
- 当前专利权人地址: JPX
- 主分类号: A61F9/007
- IPC分类号: A61F9/007 ; A61K31/409 ; A61K41/00 ; A61N5/06 ; A61P27/02 ; A61P43/00 ; A01N55/02 ; A61K31/55
摘要:
The invention provides a method to inhibit the formation of neovasculature while maintaining viability of the underlying tissue by subjecting a subject in which angiogenesis is to be inhibited to sublethal photodynamic therapy. The invention also provides a model for assessing sublethal PDT protocols to inhibit angiogenesis in particular target tissues.
公开/授权文献
- US5491284A Nude mouse model for neoplastic disease 公开/授权日:1996-02-13
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