发明授权
- 专利标题： Tissue engineered tendons and ligaments
- 专利标题（中）： 组织工程肌腱和韧带
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申请号： US905491申请日： 1997-08-04
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公开(公告)号： US6123727A公开(公告)日： 2000-09-26
- 发明人: Charles A. Vacanti , Yi Lin Cao , Robert S. Langer , Joseph P. Vacanti , Keith Paige , Joseph Upton
- 申请人： Charles A. Vacanti , Yi Lin Cao , Robert S. Langer , Joseph P. Vacanti , Keith Paige , Joseph Upton
- 申请人地址： MA MA Boston
- 专利权人： Massachusetts Institute of Technology,Cambridge Childern's Medical Center Corproration
- 当前专利权人： Massachusetts Institute of Technology,Cambridge Childern's Medical Center Corproration
- 当前专利权人地址： MA MA Boston
- 主分类号： A61F2/08
- IPC分类号： A61F2/08 ; A61L27/18 ; A61L27/38 ; A61L27/58
摘要：
Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
公开/授权文献
- US5279596A Intravascular catheter with kink resistant tip 公开/授权日：1994-01-18
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