发明授权
- 专利标题: Compounds with growth hormone releasing properties
- 专利标题(中): 具有生长激素释放特性的化合物
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申请号: US270862申请日: 1999-03-17
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公开(公告)号: US6127354A公开(公告)日: 2000-10-03
- 发明人: Bernd Peschke , Michael Ankersen , Thomas Kruse Hansen , Henning Th.o slashed.gersen
- 申请人: Bernd Peschke , Michael Ankersen , Thomas Kruse Hansen , Henning Th.o slashed.gersen
- 申请人地址: DKX Bagsvaerd
- 专利权人: Novo Nordisk A/S
- 当前专利权人: Novo Nordisk A/S
- 当前专利权人地址: DKX Bagsvaerd
- 优先权: DKX0803/96 19960722
- 主分类号: A61K31/165
- IPC分类号: A61K31/165 ; A61K31/17 ; A61K31/18 ; A61K31/27 ; A61K31/381 ; A61K31/40 ; A61K31/472 ; A61K31/495 ; A61P5/06 ; C07C237/22 ; C07C243/34 ; C07C281/06 ; C07C311/08 ; C07C311/21 ; C07D207/08 ; C07D211/06 ; C07D217/06 ; C07D241/08 ; C07D333/20 ; A61K31/135 ; A61K31/166 ; C07D333/16
摘要:
Novel peptide derivatives, compositions containing them, and their use for treating medical disorders resulting from a deficiency in growth hormone are disclosed. The peptides have the formula (I): ##STR1## wherein a, b, A, R.sup.1, L.sup.1, D, R.sup.3, R.sup.4, R.sup.2, L.sup.2, E and G are as defined in the specification. These peptides exhibit improved resistance to proteolytic degradation, and hence, improved bioavailability.
公开/授权文献
- US4935598A Automatic arc welding with filler wire 公开/授权日:1990-06-19
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