发明授权
- 专利标题： Thrombin inhibitor
- 专利标题（中）： 凝血酶抑制剂
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申请号： US200965申请日： 1998-11-30
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公开(公告)号： US6133422A公开(公告)日： 2000-10-17
- 发明人: Craig A. Rosen , Liang Cao , Mark D. Adams , Rebecca A. Fuldner
- 申请人： Craig A. Rosen , Liang Cao , Mark D. Adams , Rebecca A. Fuldner
- 申请人地址： MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： MD Rockville
- 主分类号： C07K14/81
- IPC分类号： C07K14/81 ; C12N15/12 ; C07K1/00
摘要：
There is provided a thrombin inhibitor polypeptide and DNA(RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques. The anti-thrombin polypeptide is used to treat various diseases where prevention of blood clotting is necessary and is of therapeutic value. The present invention also discloses a method of producing the anti-thrombin polypeptide and methods for its use as a pharmaceutical composition.