发明授权
- 专利标题: Stable microbubbles suspensions containing saturated lamellar phospholipids
- 专利标题(中): 稳定的微泡悬浮液含有饱和的片状磷脂
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申请号: US21150申请日: 1998-02-10
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公开(公告)号: US06136293A公开(公告)日: 2000-10-24
- 发明人: Michel Schneider , Feng Yan , Pascal Grenier, deceased , Jerome Puginier , Marie-Bernadette Barrau , Philippe Bussat , Eva Hybl , Daniel Bichon
- 申请人: Michel Schneider , Feng Yan , Pascal Grenier, deceased , Jerome Puginier , Marie-Bernadette Barrau , Philippe Bussat , Eva Hybl , Daniel Bichon
- 申请人地址: NLX
- 专利权人: Bracco International B.V.
- 当前专利权人: Bracco International B.V.
- 当前专利权人地址: NLX
- 优先权: EPX90810262 19900402
- 主分类号: A61B8/00
- IPC分类号: A61B8/00 ; A61B5/055 ; A61K9/10 ; A61K9/127 ; A61K47/10 ; A61K47/12 ; A61K47/14 ; A61K47/22 ; A61K47/24 ; A61K47/26 ; A61K47/28 ; A61K47/34 ; A61K47/36 ; A61K49/00 ; A61K49/22
摘要:
Gas or air filled microbubble suspensions in aqueous phases usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing the laminarized surfactants to air or a gas before or after admixing with an aqueous phase.
公开/授权文献
- US4768737A Helicopter control system 公开/授权日:1988-09-06
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