发明授权
- 专利标题： Preparation of beta-methyl carbapenem intermediates
- 专利标题（中）： β-甲基碳青霉烯中间体的制备
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申请号： US128638申请日： 1998-07-28
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公开(公告)号： US6143885A公开(公告)日： 2000-11-07
- 发明人: Woo-Baeg Choi , Jaemoon Lee , Joseph E. Lynch , Paul J. Reider , Ralph P. Volante
- 申请人： Woo-Baeg Choi , Jaemoon Lee , Joseph E. Lynch , Paul J. Reider , Ralph P. Volante
- 申请人地址： NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： NJ Rahway
- 主分类号： C07F7/18
- IPC分类号： C07F7/18 ; C07D205/08
摘要：
The instant invention relates to a compound of the formula: ##STR1## wherein R.sub.a and P are: (a) hydrogen,(b) methyl, or(c) a hydroxy protecting groupand an efficient process for its synthesis characterized by combining a ketoester with an acid and a catalyst at a temperature of from about 0.degree. to about 50.degree. C. and from about 0 to 500 psig to produce the above compound.
公开/授权文献
- US5447388A Modular asphaltic paving rubber blending unit and method 公开/授权日：1995-09-05
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