发明授权
- 专利标题： Peptides for the detection of HIV-1 group O
- 专利标题（中）： 用于检测HIV-1组O的肽
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申请号： US433428申请日： 1999-11-04
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公开(公告)号： US6149910A公开(公告)日： 2000-11-21
- 发明人: Robert De Leys , Jian Zheng
- 申请人： Robert De Leys , Jian Zheng
- 申请人地址： NY Rochester
- 专利权人： Ortho-Clinical Diagnostics, Inc.
- 当前专利权人： Ortho-Clinical Diagnostics, Inc.
- 当前专利权人地址： NY Rochester
- 主分类号： C07K14/16
- IPC分类号： C07K14/16 ; G01N33/569 ; A61K39/21 ; A61K38/00 ; A61K39/00 ; A61K39/12 ; A61K39/38
摘要：
This invention relates to peptides and their preparation. The peptides each have a sequence that corresponds to the immunodominant region of the HIV-1 group O gp41 envelope protein. The sequence is characterized in that it does not correspond to any known naturally occurring group O sequence or variant. Furthermore, the peptide binds anti-HIV-1 group O antibodies. There are several uses for the peptides, including the detection of antibodies produced in response to HIV-1 group O infection. The peptides may also be incorporated in mosaics and expressed recombinantly.
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