发明授权
- 专利标题: Transgenic animals expressing artificial epitope-tagged proteins
- 专利标题(中): 表达人造表位标签蛋白的转基因动物
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申请号: US31168申请日: 1998-02-26
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公开(公告)号: US6150583A公开(公告)日: 2000-11-21
- 发明人: Stanley B. Prusiner , Glenn C. Telling , Fred E. Cohen , Michael R. Scott
- 申请人: Stanley B. Prusiner , Glenn C. Telling , Fred E. Cohen , Michael R. Scott
- 申请人地址: CA Oakland
- 专利权人: The Regents of the University of California
- 当前专利权人: The Regents of the University of California
- 当前专利权人地址: CA Oakland
- 主分类号: A01K67/027
- IPC分类号: A01K67/027 ; A61K47/48 ; A61K49/00 ; C07K14/42 ; C07K14/47 ; C12N5/10 ; C12N15/09 ; C12N15/85 ; A01K67/00 ; C07H17/00 ; C12P21/06
摘要:
DNA constructs are provided of epitope-tagged proteins or protein fragments which are conveniently purified with immunoaffinity chromatography such as epitope-tagged prion proteins (PrP). Transgenic animals expressing an epitope-tagged protein are provided, including transgenic animals expressing epitope-tagged PrP. Methods for distinguishing between the conformational shapes of a protein and a convenient method for isolating a tagged protein by immunoaffinity chromatographic methods are provided.
公开/授权文献
- USD369237S Shoelace cover 公开/授权日:1996-04-30
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