Invention Grant
US6154282A Semiconductor based excitation illuminator for fluorescence and
phosphorescence microscopy
有权
用于荧光和磷光显微镜的基于半导体的激发照明器
- Patent Title: Semiconductor based excitation illuminator for fluorescence and phosphorescence microscopy
- Patent Title (中): 用于荧光和磷光显微镜的基于半导体的激发照明器
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Application No.: US374535Application Date: 1999-08-16
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Publication No.: US6154282APublication Date: 2000-11-28
- Inventor: Lothar Lilge , Peter S. Pennefather , Stephen M. Ross , Cha-Min Tang , Kai Zhang
- Applicant: Lothar Lilge , Peter S. Pennefather , Stephen M. Ross , Cha-Min Tang , Kai Zhang
- Applicant Address: Toronto
- Assignee: Cytotelesis Inc.
- Current Assignee: Cytotelesis Inc.
- Current Assignee Address: Toronto
- Main IPC: G01N21/64
- IPC: G01N21/64 ; G02B21/00 ; G02B21/06 ; H01L33/64
Abstract:
Apparatus for exciting a fluorescent or phosphorescent molecule applied to a specimen in a microscope, the molecule having a known excitation wavelength, comprises a semiconductor light source capable of emitting an output light within a preselected wavelength band correlated with the excitation wavelength of the molecule, an electronic controller coupled to the light source for controlling the intensity of the output light, and an optical system for converting the output light into an excitation beam having a pre-selected distribution of light flux suitable for illuminating the specimen. The semiconductor light source is preferably a light emitting diode or superluminescent diode. The subject invention provides for a fluorescence excitation illuminator having a long lifetime and relatively low cost. Intensity modulation or attenuation can be achieved electronically, without the need for shutters.
Public/Granted literature
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