A liquid crystal display drive circuit capable of reducing deviation between channels and realizing a liquid crystal display of a high image quality without requiring an adjustment step on a manufacturing line. A reference signal is inserted into image data and provision is made of amplifiers for processing input image data to periodically invert and supplying the same to a plurality of channels; a switch circuit; a subtraction circuit for comparing an output of a first amplifier and an output signal in a case of a non-inverted output and comparing an output of a second amplifier and the output signal in a case of an inverted output; a gate circuit for extracting only the reference signal from among output signals of the subtraction circuit and generating offset correction signals corresponding to a non-inverted mode and an inverted mode; switch circuits; integrated circuits; and an adder circuit for adding the offset correction signals corresponding to the non-inverted mode and the inverted mode to the output signal of a sample-and-hold circuit and outputting the same to the liquid crystal display panel.