发明授权
US6166051A Thiol derivatives with metallopeptidase (ACE/NEP) inhibitory activity
失效
具有金属肽酶（ACE / NEP）抑制活性的硫醇衍生物
- 专利标题： Thiol derivatives with metallopeptidase (ACE/NEP) inhibitory activity
- 专利标题（中）： 具有金属肽酶（ACE / NEP）抑制活性的硫醇衍生物
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申请号： US91415申请日： 1998-06-23
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公开(公告)号： US6166051A公开(公告)日： 2000-12-26
- 发明人: Franco Pellacini , Stefano Romagnano , Gabriele Norcini , Francesco Santangelo , Claudio Semeraro
- 申请人： Franco Pellacini , Stefano Romagnano , Gabriele Norcini , Francesco Santangelo , Claudio Semeraro
- 申请人地址： ITX Vicenza
- 专利权人： Zambon Group S.p.A.
- 当前专利权人： Zambon Group S.p.A.
- 当前专利权人地址： ITX Vicenza
- 优先权： ITXMI95A02772 19951228
- 主分类号： C07D213/55
- IPC分类号： C07D213/55 ; C07D277/30 ; C07D333/24 ; A61K31/44 ; A61K31/426 ; C07D213/04
摘要：
Compounds of formula (I) wherein R, R.sub.1, R.sub.2, R.sub.3 have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula (I) are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases. ##STR1##
公开/授权文献
- USD407545S Shoe upper 公开/授权日：1999-04-06
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