Muteins of epidermal growth factor exhibiting enhanced binding at low pH

发明授权

US06191106B1 Muteins of epidermal growth factor exhibiting enhanced binding at low pH 失效

标题翻译：表皮生长因子的突变蛋白在低pH下表现出增强的结合

请登陆查看更多内容

专利标题： Muteins of epidermal growth factor exhibiting enhanced binding at low pH
专利标题（中）： 表皮生长因子的突变蛋白在低pH下表现出增强的结合
申请号： US08619032

申请日： 1996-03-20
公开(公告)号： US06191106B1

公开(公告)日： 2001-02-20
发明人: Guy T. Mullenbach , Jeffrey M. Blaney , Steven Rosenberg
申请人： Guy T. Mullenbach , Jeffrey M. Blaney , Steven Rosenberg
主分类号： C12N1518
IPC分类号： C12N1518

Muteins of epidermal growth factor exhibiting enhanced binding at low pH

摘要：

EGF muteins in which the histidine at position 16 is replaced with a neutral or acidic amino acid exhibit activity at pHs lower than obtainable with wild type EGF.

摘要（中）：

其中16位组氨酸被中性或酸性氨基酸置换的EGF突变蛋白在低于用野生型EGF可获得的pH下表现出活性。

信息查询

Espacenet