发明授权
- 专利标题: Process for the preparation of cyclopropylglycine
- 专利标题(中): 制备环丙基甘氨酸的方法
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申请号: US09365914申请日: 1999-08-03
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公开(公告)号: US06191306B1公开(公告)日: 2001-02-20
- 发明人: Daniel John Bayston , Jonathan Luke William Griffin , Arne Gruman , Mario Eugenio Cosimino Polywka , Ronald Michael Scott
- 申请人: Daniel John Bayston , Jonathan Luke William Griffin , Arne Gruman , Mario Eugenio Cosimino Polywka , Ronald Michael Scott
- 主分类号: C07C22718
- IPC分类号: C07C22718
摘要:
Disclosed is a process for the preparation of cyclopropylglycine by a 5-step process wherein cyclopropanecarboxaldehyde is reacted with an &agr;-aminoalkylaromatic compound to obtain an imine which is reacted with a cyanide to produce an aminonitrile compound; the aminonitrile compound is hydrolyzed to the corresponding aminocarboxylic acid and finally the arylalkyl residue is removed from the amino group by hydrogenolysis.
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