An open roof construction for a vehicle having a roof opening in its fixed roof comprises a closing device for selectively closing or at least partially opening the roof opening. A driving element for the closing device comprises an outgoing driving wheel. At least one pull-push cable for providing the connection between the driving element and the closing device is guided in a cable guide and over the circumference of the driving wheel for adjustment of the cable by means of the driving element. The cable guide is provided with adaptation elements for adapting the course of the cable guide to the diameter of the driving wheel.