发明授权
US06214861B1 Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
失效
杂环羰基氨基酸羟乙基氨基磺酰胺逆转录病毒蛋白酶抑制剂
- 专利标题： Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
- 专利标题（中）： 杂环羰基氨基酸羟乙基氨基磺酰胺逆转录病毒蛋白酶抑制剂
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申请号： US09501265申请日： 2000-02-09
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公开(公告)号： US06214861B1公开(公告)日： 2001-04-10
- 发明人: Daniel P Getman , Gary A DeCrescenzo , John N Freskos , Michael L Vazquez , James A Sikorski , Balekudru Devadas , Srinivasan Nagarajan , David L Brown , Joseph J McDonald
- 申请人： Daniel P Getman , Gary A DeCrescenzo , John N Freskos , Michael L Vazquez , James A Sikorski , Balekudru Devadas , Srinivasan Nagarajan , David L Brown , Joseph J McDonald
- 主分类号： A61K314025
- IPC分类号： A61K314025
摘要：
Selected heterocycle carbonyl amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.