发明授权
US06218165B1 Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
有权
人类具有较低过敏反应的突变蛋白质以及用于构建，鉴定和产生此类蛋白质的方法
- 专利标题： Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
- 专利标题（中）： 人类具有较低过敏反应的突变蛋白质以及用于构建，鉴定和产生此类蛋白质的方法
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申请号： US09255502申请日： 1999-02-23
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公开(公告)号： US06218165B1公开(公告)日： 2001-04-17
- 发明人: David A. Estell , Fiona A. Harding
- 申请人： David A. Estell , Fiona A. Harding
- 主分类号： C12N954
- IPC分类号： C12N954
摘要：
The present invention relates to a novel improved protein mutant which produces low allergenic response in humans compared to the parent of that mutant. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein.
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