A pair of pliers with multiple functions is disclosed. The pliers have a pair of shanks pivotally engaged with each other each having a jaw formed at one end thereof, a polygon hole defined in the other end to hold a tool head, a hammer formed on the outside of one of the jaws and a chisel formed on the other. In addition, teeth and a cutting edge are formed on the face of the corresponding jaws or shanks. Consequently, the pair of pliers can be used as a hammer, a chisel or a screwdriver. This can improve the flexibility of the pair of pliers.