Invention Grant
- Patent Title: Amidine derivatives and drug carriers comprising the same
- Patent Title (中): 脒衍生物和包含其的药物载体
-
Application No.: US09202193Application Date: 1998-12-10
-
Publication No.: US06228391B1Publication Date: 2001-05-08
- Inventor: Kazuhiro Shimizu , Masashi Isozaki , Kazunori Koiwai
- Applicant: Kazuhiro Shimizu , Masashi Isozaki , Kazunori Koiwai
- Priority: JP8-111532 19960502
- Main IPC: C07C25714
- IPC: C07C25714

Abstract:
Novel amidine derivatives of the formula (1); and drug carriers such as liposomes or emulsions comprising the derivatives, which can enclose genetic materials or drugs and transfer them to cells or affected sites efficiently and safely, wherein A is an aromatic ring, R1 and R2 are the same or different and independently represent an alkyl group having any one of 10 to 25 carbon atoms, and an alkenyl group having any one of 10 to 25 carbon atoms, X and Y are the same or different and independently represent —O—, —S—, —COO—, —OCO—, —CONH—, or —NHCO—, m is 0 or 1, and n is 0 or a natural number of 1 to 6.
Information query