发明授权
US06228837B1 Endothelial monocyte activating polypeptide II: a mediator which activates host response
失效
内皮单核细胞激活多肽II:激活宿主反应的介质
- 专利标题: Endothelial monocyte activating polypeptide II: a mediator which activates host response
- 专利标题(中): 内皮单核细胞激活多肽II:激活宿主反应的介质
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申请号: US08360821申请日: 1996-10-08
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公开(公告)号: US06228837B1公开(公告)日: 2001-05-08
- 发明人: David M. Stern , Matthias Clauss , Janet Kao , Mark Kayton , Steven K. Libutti
- 申请人: David M. Stern , Matthias Clauss , Janet Kao , Mark Kayton , Steven K. Libutti
- 主分类号: A61K3800
- IPC分类号: A61K3800
摘要:
This invention provides a purified endothelial monocyte activating polypeptide (EMAP II). It further provides a method of obtaining purified endothelial monocyte activating polypeptide (EMAP II), a method of making antibodies to it and a method of detecting it. This invention also provides an effector cell activating protein which contains an amino acid sequence homologous to RIGRIVT and a method of detecting same. This invention also provides a method of treating a tumor in a subject by administering an effective dose of endothelial monocyte activating polypeptide (EMAP II).
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