发明授权
- 专利标题: N-substituted azaheterocyclic carboxylic acids and esters thereof
- 专利标题(中): N-取代的氮杂环状羧酸及其酯
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申请号: US09055574申请日: 1998-04-06
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公开(公告)号: US06239148B1公开(公告)日: 2001-05-29
- 发明人: Florenzio Zaragossa Dörwald , Knud Erik Andersen , Rolf Hohlweg , Peter Madsen , Tine Krogh Jørgensen , Uffe Bang Olsen , Henrik Sune Andersen , Svend Treppendahl , Polivka Zdenék , Silhánková Alexandra , Sindelár Karel
- 申请人: Florenzio Zaragossa Dörwald , Knud Erik Andersen , Rolf Hohlweg , Peter Madsen , Tine Krogh Jørgensen , Uffe Bang Olsen , Henrik Sune Andersen , Svend Treppendahl , Polivka Zdenék , Silhánková Alexandra , Sindelár Karel
- 优先权: DK0019/94 19940104; DK1290/94 19941109; DK0405/95 19950407; DK1005/95 19950911
- 主分类号: A61K31451
- IPC分类号: A61K31451
摘要:
The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
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