发明授权
US06242175B1 Methods and means relating to retrotransposon and retroviral integration
失效
与反转录转座子和逆转录病毒整合相关的方法和手段
- 专利标题: Methods and means relating to retrotransposon and retroviral integration
- 专利标题(中): 与反转录转座子和逆转录病毒整合相关的方法和手段
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申请号: US09341515申请日: 1999-07-12
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公开(公告)号: US06242175B1公开(公告)日: 2001-06-05
- 发明人: Stephen Philip Jackson , Jessica Anne Downs
- 申请人: Stephen Philip Jackson , Jessica Anne Downs
- 优先权: GB9700574 19970113
- 主分类号: C12Q170
- IPC分类号: C12Q170
摘要:
Ku(Ku70 and Ku80) of yeast and mammalian cells and other components of the Ku-associated DNA repair pathway are involved in retrotransposon and retroviral integration into cellular nucleic acids. Agents which inhibit activity of the pathway are useful for inhibition of retroviruses. Such agents are obtainable using assays involving the Ku-associated DNA repair pathway and one or more components thereof.
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