- 专利标题： GABA and L-glutamic acid analogs for antiseizure treatment
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申请号： US09244676申请日： 1999-02-04
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公开(公告)号： US06255345B1公开(公告)日： 2001-07-03
- 发明人: Richard B. Silverman , Ryszard Andruszkiewicz , Po-Wai Yuen , Denis Martin Sobieray , Lloyd Charles Franklin , Mark Alan Schwindt
- 申请人： Richard B. Silverman , Ryszard Andruszkiewicz , Po-Wai Yuen , Denis Martin Sobieray , Lloyd Charles Franklin , Mark Alan Schwindt
- 主分类号： A61K31195
- IPC分类号： A61K31195
摘要：
A compound of the formula wherein R1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R2 is hydrogen or methyl; and R3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
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