发明授权
- 专利标题: 2-oxoimidazole derivatives
- 专利标题(中): 2-氧代咪唑衍生物
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申请号: US09424114申请日: 1999-11-19
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公开(公告)号: US06258825B1公开(公告)日: 2001-07-10
- 发明人: Satoshi Ozaki , Hiroshi Kawamoto , Yoshiki Ito , Kaori Hirano , Kyoko Hayashi , Yoshikazu Iwasawa
- 申请人: Satoshi Ozaki , Hiroshi Kawamoto , Yoshiki Ito , Kaori Hirano , Kyoko Hayashi , Yoshikazu Iwasawa
- 优先权: JP9-157913 19970530; JP9-191859 19970702
- 主分类号: A61K31454
- IPC分类号: A61K31454
摘要:
The present invention relates to a compound represented by Formula [I] wherein represents an aromatic carbo- or heterocyclic ring which may have a substituent; Cy represents a mono-, bi- or tricyclic aliphatic carbocyclic group having 3 to 20 carbon atoms, which may have a substituent; represents a mono- or bicyclic aliphatic nitrogen-containing heterocyclic group having 3 to 14 carbon atoms, which may have a substituent; R1 represents a hydrogen atom, a lower alkenyl group, a lower alkynyl group, a cyclo(lower alkyl) group, an amino group, a lower alkylamino group, a di(lower alkyl)-amino group, a hydroxyl group, a lower alkoxy group, a carboxyl group, a lower alkoxycarbonyl group, a carbamoyl group, a lower alkylcarbamoyl group or a di(lower alkyl)carbamoyl group, or a lower alkyl group which may have a substituent; and R2 represents a hydrogen atom or a lower alkyl group, a salt or ester thereof, a production process for the same, and an analgesic, a reliever against tolerance to a narcotic analgesic represented by morphine, a reliever against dependence on a narcotic analgesic represented by morphine, an analgesic enhancer, an antiobestic, a drug for ameliorating brain function, a remedy for schizophrenia, a remedy for Parkinsonism, a remedy for chorea, an antidepressant, a remedy for diabetes insipidus, a remedy for polyuria, or a remedy for hypotension, comprising an effective ingredient of the same.
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