发明授权
US06262095B1 Use of tricyclic derivatives of 1,4-dihydro-1,4-dioxo-1H-naphthalene, novel compounds obtained and their application in theraphy
失效
使用1,4-二氢-1,4-二氧代-1H-萘的三环衍生物,获得的新化合物及其在治疗中的应用
- 专利标题: Use of tricyclic derivatives of 1,4-dihydro-1,4-dioxo-1H-naphthalene, novel compounds obtained and their application in theraphy
- 专利标题(中): 使用1,4-二氢-1,4-二氧代-1H-萘的三环衍生物,获得的新化合物及其在治疗中的应用
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申请号: US09043831申请日: 1998-10-14
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公开(公告)号: US06262095B1公开(公告)日: 2001-07-17
- 发明人: Odile Boutherin-Falson , Stéphanie Desquand-Billiald , Anita Favrou , Michel Finet , Olivier Tembo , Jean-Luc Torregrosa , Sylvie Yannic-Arnoult , Florence Domagala-Le Marquer
- 申请人: Odile Boutherin-Falson , Stéphanie Desquand-Billiald , Anita Favrou , Michel Finet , Olivier Tembo , Jean-Luc Torregrosa , Sylvie Yannic-Arnoult , Florence Domagala-Le Marquer
- 优先权: FR9514683 19951212
- 主分类号: C07D23502
- IPC分类号: C07D23502
摘要:
The invention concerns the therapeutic use of tricyclic salts and their pharmaceutically acceptable salts having the general formula: in which: A is either a sulfur atom, an oxygen atom, or an R3N radical where R3 is a hydrogen atom, a C1-C5 alkyl radical, or a substituted or unsubstituted aromatic ring, or a substituted or unsubstituted heteroaromatic ring. R1 is either a C1-C5 alkyl radical, or an R4NH radical where R4 is a hydrogen atom, a C1-C5 alkyl radical, or a substituted or unsubstituted aromatic ring, or a substituted or unsubstituted heteroaromatic ring, or an aromatic ring that may or may not be substituted by one or more acceptor or donor groups, or a heteroaromatic ring having one or more heteroatoms, which may or may not be substituted by acceptor or donor groups. R2 is a hydrogen atom, halogen atom, a C1-C5 alkyl radical, an oxygen atom that may or may not be substituted by a C1-C5 alkyl radical, or an NR5R5, radical where R5 and R5, are, independently of each other, a hydrogen atom, an oxygen atom or monovalent C1-C5 organic radicals.
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