发明授权
- 专利标题: Controlled-release pharmaceutical preparation comprising an ACE inhibitor as active ingredient
- 专利标题(中): 包含ACE抑制剂作为有效成分的控释药物制剂
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申请号: US09460055申请日: 1999-12-13
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公开(公告)号: US06267990B1公开(公告)日: 2001-07-31
- 发明人: Wilfried Fischer , Karin Klokkers , Renate Oppelt
- 申请人: Wilfried Fischer , Karin Klokkers , Renate Oppelt
- 优先权: DE19724696 19970612
- 主分类号: A61K916
- IPC分类号: A61K916
摘要:
The invention relates to a pharmaceutical preparation which comprises or consists of the following components: (i) an initial dose of active ingredient, which is provided by the active ingredient together with optional excipients, (ii) a first delayed-release type of pellet, in which the active ingredient and optional excipients are covered with a coating, and (iii) a second delayed-release type of pellet, in which the active ingredient and optional excipients are again covered with a coating, wherein the active ingredient is an ACE inhibitor, and wherein the amounts of the coatings according to (ii) and (iii) are present in a ratio, based on weight, within the range of from 1:2 to 1:7.
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