发明授权
- 专利标题: HIV protease inhibitors
- 专利标题(中): HIV蛋白酶抑制剂
-
申请号: US08478600申请日: 1995-06-07
-
公开(公告)号: US06271235B1公开(公告)日: 2001-08-07
- 发明人: Bruce A. Dressman , James E. Fritz , Stephen W. Kaldor , Vincent J. Kalish , Siegfried Heinz Reich , Michael J. Rodriguez , Timothy A. Shepherd , John H. Tatlock , Louis Nickolaus Jungheim
- 申请人: Bruce A. Dressman , James E. Fritz , Stephen W. Kaldor , Vincent J. Kalish , Siegfried Heinz Reich , Michael J. Rodriguez , Timothy A. Shepherd , John H. Tatlock , Louis Nickolaus Jungheim
- 主分类号: A61K31495
- IPC分类号: A61K31495
摘要:
HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.