发明授权
- 专利标题： Preparation of biodegradable, biocompatible microparticles containing a biologically active agent
- 专利标题（中）： 制备含有生物活性剂的可生物降解的生物相容性微粒
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申请号： US09578717申请日： 2000-05-26
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公开(公告)号： US06290983B1公开(公告)日： 2001-09-18
- 发明人: Michael E. Rickey , J. Michael Ramstack , Danny H. Lewis
- 申请人： Michael E. Rickey , J. Michael Ramstack , Danny H. Lewis
- 主分类号： A61F200
- IPC分类号： A61F200
摘要：
A method for preparing biodegradable, biocompatible microparticles. A first phase is prepared that includes a biodegradable, biocompatible polymer, an active agent, and a solvent. A second phase is prepared. The first and second phases are combined to form an emulsion in which the first phase is discontinuous and the second phase is continuous. The discontinuous first phase is separated from the continuous second phase. The residual level of solvent in the discontinuous first phase is reduced to less than about 2% by weight.
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