An isolation system having: an isolation string, wherein the isolation string has a packing assembly which secures the isolation string in a wellbore casing, wherein the isolation string has a production screen which allows production fluid to pass into the isolation string; an isolation sleeve which slides within the isolation string between open and closed positions, wherein the open position allows fluid communication between the production screen and an interior portion of the isolation string and the closed position prevents fluid communication between the production screen and an interior portion of the isolation string, wherein the isolation sleeve comprises at least one isolation valve which is coupled within the isolation sleeve, wherein the at least one isolation valve is movable between open and closed positions; a locking device which locks and unlocks the isolation sleeve in an open position, wherein the locking device comprises a trigger that secures the isolation sleeve to the isolation string before the trigger is activated and releases the isolation sleeve from the isolation string after the trigger is activated, wherein the trigger comprises: a piston collar having a solid cylindrical portion attached to the isolation sleeve and a finger portion having at least one finger, wherein the at least one finger has a head at a distal end; and at least one recess in the isolation string, wherein the head of the at least one finger is engaged in the at least one recess; a cylindrically shaped pop lock positioned adjacent the head of the at least one finger so that the head is between the pop lock and the recess, wherein the pop lock secures the head relative to the recess; and a latch attached to the service tool which couples with the pop lock, wherein the trigger is activated by removing the pop lock from the position adjacent the head; and an activation tool which allows the isolation sleeve to move to a closed position, wherein the activation tool is a piston driven by a hydrostatic chamber which comprises lower pressure within the hydrostatic chamber than without, and wherein the piston moves the isolation sleeve from the open to the closed position.