An actuating device for automatic operation of a gear change in a transmission that produces a change in predetermined translation ratios of the gear change transmission in any desired sequence comprises first and second drives that are in active connection with a selector shaft. The first drive is connected to the selector shaft via a guide mechanism which comprises at least one constraint guide that corresponds to a shifting path. The second drive is in active connection with the selector shaft for providing an operating force in the axial direction and an operating force in the circumferential direction of the selector shaft. The resulting movement depends on the operating position of the guide mechanism.