发明授权
- 专利标题: 1-aza-2-alkyl-6-aryl-cycloalkane compounds
- 专利标题(中): 1-氮杂-2-烷基-6-芳基 - 环烷烃化合物
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申请号: US09561646申请日: 2000-05-02
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公开(公告)号: US06323222B1公开(公告)日: 2001-11-27
- 发明人: Sylvain Rault , Olivier Renault , Jean Guillon , Patrick Dallemagne , Pierre Renard , Bruno Pfeiffer , Pierre Lestage , Marie-Cécile Lebrun
- 申请人: Sylvain Rault , Olivier Renault , Jean Guillon , Patrick Dallemagne , Pierre Renard , Bruno Pfeiffer , Pierre Lestage , Marie-Cécile Lebrun
- 优先权: FR9905600 19990503
- 主分类号: A61K31445
- IPC分类号: A61K31445
摘要:
Compound of formula (I): wherein: n represents 0 or 1, R1 represents hydrogen, arylalkyl, alkyl, acyl, alkoxycarbonyl, arylalkoxycarbonyl or trifluoroacetyl, R2 represents alkyl, X represents oxygen, chlorine, OR3, SR4 or NOR5, R3 represents hydrogen, alkyl, acyl, alkoxycarbonyl or arylalkoxycarbonyl, R4 represents hydrogen, alkyl or aryl, R5 represents hydrogen or optionally substituted alkyl, represents a single or double bond, Ar represents aryl or heteroaryl, its isomers and addition salts thereof with a pharmaceutically acceptable acid, and medicinal products containing the same which are useful as facilitators of memory and cognition and antalgic agents.
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