发明授权
- 专利标题: Process for preparing substituted benzoyl cyanide amidinohydrazones
- 专利标题(中): 取代苯甲酰氰化脒基腙的制备方法
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申请号: US09789634申请日: 2001-02-22
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公开(公告)号: US06329521B2公开(公告)日: 2001-12-11
- 发明人: Vladimir Nadaka , Jael Lexmer , Joseph Kaspi
- 申请人: Vladimir Nadaka , Jael Lexmer , Joseph Kaspi
- 优先权: IL134730 20000225
- 主分类号: C07C25517
- IPC分类号: C07C25517
摘要:
The present invention provides a process for preparing a compound of the general formula (I): wherein R1 to R5 are independently selected from hydrogen, halogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl or C1-6 alkoxy, all optionally substituted by one or more of halogen, hydroxy and aryl groups, as well as being independently selected from amino, mono- or disubstituted amino, alkenyloxy, acyl, acyloxy, cyano, nitro, aryl and alkylthio groups, which process comprises reacting a compound of the general formula (II): wherein R1 to R5 are as defined in formula (I), with aminoguanidine bicarbonate in a mixture of a water-soluble solvent and polyphosphoric acid.
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