发明授权
- 专利标题： Streptogramins for preparing same by mutasynthesis
- 专利标题（中）： 链霉素及其制备方法
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申请号： US08765907申请日： 1997-03-20
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公开(公告)号： US06352839B1公开(公告)日： 2002-03-05
- 发明人: Véronique Blanc , Denis Thibaut , Nathalie Bamas-Jacques , Francis Blanche , Joël Crouzet , Jean-Claude Barriere , Laurent Debussche , Alain Famechon , Jean-Marc Paris , Gilles Dutruc-Rosset
- 申请人： Véronique Blanc , Denis Thibaut , Nathalie Bamas-Jacques , Francis Blanche , Joël Crouzet , Jean-Claude Barriere , Laurent Debussche , Alain Famechon , Jean-Marc Paris , Gilles Dutruc-Rosset
- 优先权： FR9408478 19940708
- 主分类号： C12P100
- IPC分类号： C12P100
摘要：
The invention provides a method for preparing streptogramins using genetically-modified microorganisms to influence the biosynthesis of at least one of the precursors of the group B streptogramins. Cultures of the genetically-modified microorganisms are supplemented with a least one precursor that is different from the streptogramin precursor whose biosynthesis is altered and the streptogramins produced are recovered.
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