发明授权
- 专利标题: Individually addressable micro-electromagnetic unit array chips
- 专利标题(中): 单独寻址微电磁单元阵列芯片
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申请号: US09399299申请日: 1999-09-17
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公开(公告)号: US06355491B1公开(公告)日: 2002-03-12
- 发明人: Yuxiang Zhou , Litian Liu , Ken Chen , Depu Chen , Jia Wang , Zewen Liu , Zhimin Tan , Junquan Xu , Xiaoshan Zhu , Xuezhong He , Wenzhang Xie , Zhiming Li , Xiumei Liu
- 申请人: Yuxiang Zhou , Litian Liu , Ken Chen , Depu Chen , Jia Wang , Zewen Liu , Zhimin Tan , Junquan Xu , Xiaoshan Zhu , Xuezhong He , Wenzhang Xie , Zhiming Li , Xiumei Liu
- 优先权: CN99104113A 19990315; CN99120320A 19990916
- 主分类号: G01N33543
- IPC分类号: G01N33543
摘要:
This invention provides electromagnetic chips and electromagnetic biochips having arrays of individually addressable micro-electromagnetic units, as well as methods of utilizing these chips for directed manipulation of micro-particles and micro-structures such as biomolecules and chemical reagents. An electromagnetic biochip comprises an individually addressable micro-electromagnetic unit chip with ligand molecules immobilized on its surface. By controlling the electromagnetic field at each unit of the array and combining this control with magnetic modification of biomolecules, these chips can be used for directed manipulation, synthesis and release of biomolecules in order to increase sensitivity of biochemical or chemical analysis and reduce assay time. Other advantages with these chips include minimized damages to biological molecules and increased reproducibility of assay results.
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