发明授权
US06387674B1 Catalytic monoclonal antibodies with protease activity for selective lysis of protein component of plaques aggregates pathological conditions
失效
具有蛋白酶活性的催化单克隆抗体用于选择性裂解斑块蛋白质组分聚集病理状况
- 专利标题： Catalytic monoclonal antibodies with protease activity for selective lysis of protein component of plaques aggregates pathological conditions
- 专利标题（中）： 具有蛋白酶活性的催化单克隆抗体用于选择性裂解斑块蛋白质组分聚集病理状况
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申请号： US09463724申请日： 2000-02-14
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公开(公告)号： US06387674B1公开(公告)日： 2002-05-14
- 发明人: Silvia Trasciatti , Sergio Rosini
- 申请人： Silvia Trasciatti , Sergio Rosini
- 优先权： ITMI97A1826 19970730
- 主分类号： C12N900
- IPC分类号： C12N900
摘要：
Catalytic monoclonal antibodies (abzymes) with selective protease activity in the pathologies characterized by the presence of plaques and fibrillar aggregates with protein component; methods for the preparation thereof and the use thereof as medicaments in the treatment of pathologies such as Alzheimer's disease, amyloidosis, atherosclerosis, prions diseases.
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