发明授权
- 专利标题: Azole compounds, their production and their use
- 专利标题(中): 唑类化合物,其生产及其用途
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申请号: US09381479申请日: 1999-09-20
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公开(公告)号: US06407129B1公开(公告)日: 2002-06-18
- 发明人: Katsumi Itoh , Tomoyuki Kitazaki , Kenji Okonogi
- 申请人: Katsumi Itoh , Tomoyuki Kitazaki , Kenji Okonogi
- 优先权: JP9-080863 19970331; JP9-182395 19970708; JP9-337299 19971208
- 主分类号: A61K3141
- IPC分类号: A61K3141
摘要:
A quaternized nitrogen-containing imidazol-1-yl or 1,2,4-triazol-1-yl compound wherein one of the nitrogen atoms constituting an azole ring is quaternized with a substituent capable of being eliminated in vivo and the substituent can be eliminated in vivo to be converted into an antifungal azole compound, has an improved solubility in water, can advantageously be applied to injection, has an improved internal absorption and can be expected to have a good effect for the treatment or prevention of disease.