发明授权
US06413776B1 High throughput screening of gene function using adenoviral libraries for functional genomics applications
失效
基因功能的高通量筛选使用腺病毒文库进行功能基因组学应用
- 专利标题： High throughput screening of gene function using adenoviral libraries for functional genomics applications
- 专利标题（中）： 基因功能的高通量筛选使用腺病毒文库进行功能基因组学应用
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申请号： US09097239申请日： 1998-06-12
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公开(公告)号： US06413776B1公开(公告)日： 2002-07-02
- 发明人: Ronald Vogels , Abraham Bout , Helmuth H. G. van Es , Govert Shouten
- 申请人： Ronald Vogels , Abraham Bout , Helmuth H. G. van Es , Govert Shouten
- 主分类号： C12N510
- IPC分类号： C12N510
摘要：
Novel adenovirus vectors and methods for their use are provided to determine the function of the product(s) of one or more sample nucleic acids. The sample nucleic acids are synthetic oligonucleotides, DNA, or cDNA and encode polypeptides, antisense nucleic acids or GSEs. The sample nucleic acids are expressed in a host by recombinant adenovirus vectors to alter at least one phenotype of the host. The altered phenotype(s) is identified as a means to assign a biological function to the product(s) encoded by the sample nucleic acid(s).
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