发明授权
US06414179B1 Alpha-and beta-substituted trifluoromethyl ketones as phospholipase inhibitors
有权
α-和β-取代的三氟甲基酮作为磷脂酶抑制剂
- 专利标题： Alpha-and beta-substituted trifluoromethyl ketones as phospholipase inhibitors
- 专利标题（中）： α-和β-取代的三氟甲基酮作为磷脂酶抑制剂
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申请号： US09816574申请日： 2001-03-23
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公开(公告)号： US06414179B1公开(公告)日： 2002-07-02
- 发明人: Jacques Banville , Anne Marinier , Yonghua Gai , Serge Plamondon , Stephan Roy , Neelakantan Balasubramanian
- 申请人： Jacques Banville , Anne Marinier , Yonghua Gai , Serge Plamondon , Stephan Roy , Neelakantan Balasubramanian
- 主分类号： C07C26100
- IPC分类号： C07C26100
摘要：
Inhibitors of the cytosolic phospholipase A2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula where X, Z, R1, R2, R3, R4, Ra and Rb are as defined in the specification.
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