发明授权
US06419945B1 Buffered resorbable internal fixation devices and methods for making material therefore
有权
因此,缓冲可再吸收的内固定装置和制造材料的方法
- 专利标题: Buffered resorbable internal fixation devices and methods for making material therefore
- 专利标题(中): 因此,缓冲可再吸收的内固定装置和制造材料的方法
-
申请号: US09166508申请日: 1998-10-05
-
公开(公告)号: US06419945B1公开(公告)日: 2002-07-16
- 发明人: Joseph D. Gresser , Debra J. Trantolo , Robert Langer , Alexander M. Klibanov , Donald L. Wise
- 申请人: Joseph D. Gresser , Debra J. Trantolo , Robert Langer , Alexander M. Klibanov , Donald L. Wise
- 主分类号: A61F202
- IPC分类号: A61F202
摘要:
An internal fixation device and a bioerodible implantable material useful therefor comprise a bioerodible polymer that produces acidic products or low molecular weight resorbable fragments upon hydrolytic degradation, and a buffering or neutralizing agent in sufficiently high concentration to moderate the rate of change of pH of said bioerodible material during bioerosion. The buffering or neutralizing agent acts to reduce the inflammatory foreign body response generated by the acidic products and reduces the sterile abscess condition that occurs at the site of the bioerodible implant materials of the prior art. Internal fixation devices (IFDs) according to the invention are useful, for example, for the repair, replacement or reconstruction of damaged bone in any area of the body.
信息查询