发明授权
- 专利标题： Reverse micelles for delivery of nucleic acids
- 专利标题（中）： 用于递送核酸的反胶束
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申请号： US09354957申请日： 1999-07-16
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公开(公告)号： US06429200B1公开(公告)日： 2002-08-06
- 发明人: Sean D. Monahan , Jon A. Wolff , Paul M. Slattum , James E. Hagstrom , Vladimir G. Budker
- 申请人： Sean D. Monahan , Jon A. Wolff , Paul M. Slattum , James E. Hagstrom , Vladimir G. Budker
- 主分类号： A61K317105
- IPC分类号： A61K317105
摘要：
A complex is described for delivery to a cell comprising inserting a nucleic acid into a reverse micelle. The reverse micelle has the property to compact the nucleic acid for easier delivery. Other molecules are used to interact with the nucleic acid—micelle complex to further enhance delivery such as a surfactant having a disulfide bond.
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