发明授权
US06468532B1 Methods of treating inflammatory diseases with anti-IL-8 antibody fragment-polymer conjugates
失效
用抗IL-8抗体片段 - 聚合物缀合物治疗炎性疾病的方法
- 专利标题： Methods of treating inflammatory diseases with anti-IL-8 antibody fragment-polymer conjugates
- 专利标题（中）： 用抗IL-8抗体片段 - 聚合物缀合物治疗炎性疾病的方法
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申请号： US09234340申请日： 1999-01-20
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公开(公告)号： US06468532B1公开(公告)日： 2002-10-22
- 发明人: Vanessa Hsei , Iphigenia Koumenis , Steven Leong , Leonard Presta , Zahra Shahrokh , Gerardo Zapata
- 申请人： Vanessa Hsei , Iphigenia Koumenis , Steven Leong , Leonard Presta , Zahra Shahrokh , Gerardo Zapata
- 主分类号： A61K3944
- IPC分类号： A61K3944
摘要：
Provided are methods for treating inflammatory diseases in a patient comprising administering to the patient an effective amount of a conjugate consisting essentially of one or more antibody fragments covalently attached to one or more nonproteinaceous polymer molecules, wherein at least one antibody fragment comprises an antigen binding site that binds to human IL-8, and wherein the apparent size of the conjugate is at least about 500 kD.
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