- 专利标题： Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same
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申请号： US09487716申请日： 2000-01-19
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公开(公告)号： US06475763B1公开(公告)日： 2002-11-05
- 发明人: Maty Ayal-Hershkovitz , Haim Moskowitz , Daphna Miron , Ayelet Gilboa , Madlene Mimon , Hanna Ben-Artzi , Oron Yacoby-Zeevi , Iris Pecker , Yoav Peleg , Yinon Shlomi
- 申请人： Maty Ayal-Hershkovitz , Haim Moskowitz , Daphna Miron , Ayelet Gilboa , Madlene Mimon , Hanna Ben-Artzi , Oron Yacoby-Zeevi , Iris Pecker , Yoav Peleg , Yinon Shlomi
- 主分类号： C12Q100
- IPC分类号： C12Q100
摘要：
Bacterial, yeast and animal cells and methods for overexpressing recombinant heparanase in cellular systems, methods of purifying recombinant heparanase therefrom and modified heparanase species which serve as precursors for generating highly active heparanase by proteolysis.
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